Key Aspects: MSC Cruises’ MSC Opera is set to deploy year-round to the Dominican Republic. The ship will begin sailing from La Romana in November 2026. The cruise line previously offered only seasonal voyages in the Southern Caribbean. MSC Cruises is gearing up to deploy its MSC Opera to the Southern Caribbean on a year-round basis starting in November 2026. The 2,150-guest ship, a Lirica-class vessel that entered service in 2004, will begin sailing 7- and 14-night cruises from La Romana, Dominican Republic, a growing port roughly 75 miles from the island’s capital, Santo D...

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