Joe Manganiello is pulling back the curtain on a harrowing seven-year health battle that nearly killed him — and reshaped every corner of his life. The actor details his undiagnosed autoimmune illness in his debut memoir, Bloodlines, released in October 2026. In the book, Manganiello recounts collapsing on a Wilmington, North Carolina, film set in 2016 and needing emergency surgery to remove his entire large intestine before a grueling recovery. While Manganiello never received a formal diagnosis, the former True Blood star he’s now symptom-free and no longer takes medicati...