Grey’s Anatomy continues to thrive on ABC after more than two decades, which has required some changes — including when it comes to the cast. The medical drama, which premiered in 2005, follows employees at Grey Sloan Memorial Hospital. Over the years, the cast at the center of the show has changed as characters have come and gone — with many dying on screen due to various accidents in the workplace. Season 23 will premiere in October 2026 and picks up after numerous cast exits. Fans have previously expressed concern about major changes, which showrunner Meg Marinis has add...