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Ohio State vs. Ball State Prediction, Odds, Pick For College Football Week 1

Ohio State vs. Ball State Prediction, Odds, Pick For College Football Week 1

The No. 1 Ohio State Buckeyes will host the Ball State Cardinals on Saturday in a Week 1 college football matchup on Big Ten Network. The Buckeyes are coming off a 12-2 season in 2025, losing their final two games against eventual national champion Indiana in the Big Ten Championship Game and runner-up Miami in the College Football Playoff quarterfinals. Ohio State lost seven defensive starters from last season, including three top-11 picks in this spring's NFL Draft. Those are significant losses from a 2025 defense that ranked No. 1 in the FBS in scoring defense (9.3 PPG), total defense (219....

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