College football kicked off last weekend with Bill Belichick and North Carolina surprising TCU as 9-point underdogs, winning in Ireland in the first game of the 2026 season. With the focus of this column once a week being on dangerous underdogs who have a chance to defy the odds and get a win, perhaps another ACC team can follow suit and surprise their favored opponent this weekend. On Sunday night, No. 24 Louisville is a 7-point underdog for its opener, as the Cardinals take on No. 9 Ole Miss in Nashville, Tennessee. Let's get into my pick. This page may contain affiliate links to legal sport...
Favorite 'Dogs: Back 'New-look' Louisville To Make Statement Against Ole Miss
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